Big changes come to The Deuce as Gene sees opportunity in the city's public health crisis. Vincent looks to get out from under the mob's thumb and makes peace with Abby, who decides to pursue a new future. Candy makes a critical choice in her relationship with Hank. Harvey speaks his mind about Candy's film. Alston recognizes the truth of Midtown's redevelopment. Melissa makes a commitment, while Loretta takes on a big responsibility.