After a tip reveals there’s a mole within the FBI’s New York Office, the team must hunt for the operative while facing extreme scrutiny from Inspector Fischer. The team’s deepest secrets threaten to be exposed, and everyone is a potential suspect – but some, especially Jane Doe have more to hide.
After a disturbed Iraq War vet shoots up a military base, the team exposes a sinister plot. As Jane and Weller race to stop a single-minded scientist, Jane recalls her own mysterious military past and contemplates a new relationship with Oscar.
Jane reels from a series of massive revelations about her tattoos and grapples with whether to trust Oscar. Meanwhile, a tattoo leads the team to a shocking discovery in the Black Sea.
In the thrilling mid-season finale the team goes after a group of sleeper spies that have just been activated and race to stop a slew of assassinations.
Jane and Weller go undercover as a world-class assassin couple to prevent deadly information from getting into the wrong hands. The intimate assignment draws them closer than ever. Meanwhile, David embarks on a solo mission to win Patterson back, and Carter clashes with Mayfair over how to handle a dangerous individual.
After a police officer is murdered, Patterson unlocks a disturbing tattoo that appears to have predicted his killing, and the team chases a violent clue trail to stop further attacks. Mayfair reveals secrets from her past to Weller, seriously testing their relationship.
One of Jane’s tattoos sends the team to a remote location where they find themselves face to face with a dangerous criminal in a case that puts Jane and Weller’s strained relationship to the test and threatens to expose Mayfair’s secrets. Meanwhile, Patterson breaks the rules to solve a tattoo puzzle.
When an assassination leads the team to a dangerous app that allows criminals to track government vehicles, they have to work with the app’s surprising creator to take it down. Jane and Weller attempt to keep their relationship professional. Zapata struggles with a moral issue.
After a seemingly straightforward hostage situation turns out to have deeper international implications, the CIA and FBI find themselves racing against each other to apprehend the same criminal with a dark history. Carter expresses concern about Jane’s trustworthiness, causing friction with Mayfair and testing Reade’s loyalty to the team. Meeting Weller’s family proves overwhelming for Jane as she grapples with her identity.
Patterson and her puzzle-expert boyfriend, David, decode a tattoo clue that sends the team to the Centers for Disease Control (CDC). While at the CDC, the team discovers a hidden message on Jane’s body that uncovers a plot that could have catastrophic global consequences. Meanwhile, Jane and Weller grow closer.